The process of EDC-NHS cross-linking of reconstituted collagen fibres increases collagen fibrillar order and alignment
نویسندگان
چکیده
منابع مشابه
The process of EDC-NHS Cross-linking of reconstituted collagen fibres increases collagen fibrillar order and alignment.
We describe the production of collagen fibre bundles through a multi-strand, semi-continuous extrusion process. Cross-linking using an EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide), NHS (N-hydroxysuccinimide) combination was considered. Atomic Force Microscopy (AFM) and Raman spectroscopy focused on how cross-linking affected the collagen fibrillar structure. In the cross-linked fibres, a...
متن کاملcollagen cross-linking
patients with keratoconus constitute a large proportion of patients suffering from anterior segment disorders. as of this time, however, its pathogenesis has not yet been elucidated. a reduction in cross-link between collagen molecules has been observed in keratoconic eyes as compared to normal ones. present approaches only address refractive errors resulting from the abnormal abnormal corneal ...
متن کاملComparative Study of the Effect of Indomethacin and Acetaminophen on Pain after Collagen Cross-Linking Surgery
Introduction: One of the surgeries that needs to be considered after pain and discomfort is corneal cross-linking of the cornea. The aim of this study was to compare the effect of indomethacin and acetaminophen oral surgery before surgery on postoperative pain in the patients undergoing collagen cross-linking surgery. Methods: The present study was a double-blind clinical trial study that was ...
متن کاملReconstituted collagen fibrils. Fibrillar and molecular stability of the collagen upon maturation in vitro.
During the maturation in vitro of reconstituted collagen fibrils prepared from rat skin, the mechanical and thermal stability of collagen increased and the pepsin-solubility decreased. At the same time a larger fraction of the pepsin-soluble collagen attained a lower molecular thermal stability that resulted in a biphasic thermal transition of the soluble collagen. Type-I collagen, with a simil...
متن کاملImmobilization of the Alkaline Phosphatase on Collagen Surface via Cross-Linking Method
Background: Collagen, the most abundant protein in the human body, and as an extracellular matrix protein, has an important role in the fiber formation. This feature of the collagen renders establishment of the structural skeleton in tissues. Regarding specific features associated with the collagen, such as, formation of the porous structure, permeability and hydrophilicity, it can also be use...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: APL Materials
سال: 2015
ISSN: 2166-532X
DOI: 10.1063/1.4900887